Do not let Steam auto-update. Set Fallout 4 to "Only update this game when I launch it" and always launch via your mod manager (Vortex/MO2) which bypasses Steam’s launcher.
Game Updates & Modding If you’ve launched Fallout 4 on PC recently and glanced at the bottom-left corner of the main menu, you’ve seen it staring back at you: 1.10.163 . fallout 4 version 1.10.163
*Fallout 4 Version 1.10.163: The "Creation Club" Patch That Changed Modding Forever Do not let Steam auto-update
A split screenshot—left side showing the vanilla Fallout 4 menu with "1.10.163" in the corner, right side showing a heavily modded game with the F4SE version number visible. fallout 4 version 1.10.163